Article
Gene expression profiling in whole blood identifies distinct biological pathways associated with obesity
1 Dec 2010
Abstract excerpt
BACKGROUND: Obesity is reaching epidemic proportions and represents a significant risk factor for cardiovascular disease, diabetes, and cancer. METHODS: To explore the relationship between increased body mass and gene expression in blood, we conducted whole-genome expression profiling of whole blood from seventeen obese and seventeen well matched lean subjects. Gene expression data was analyzed at the individual...
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