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Article

The molecular basis of low activity levels of coagulation factor VII: a Brazilian cohort.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Sept 2015

Rabelo F Y, Jardim L L, Landau M B, Gadelha T, Corrêa M F B, Pereira I F M, Rezende S M

Abstract excerpt

Inherited factor VII (FVII) deficiency is the most common among the rare bleeding disorders. It is transmitted as an autosomal recessive inheritance, due to mutations in the FVII gene (F7). Molecular studies of FVII deficiency are rare in non-Caucasian populations. The aim of the study was to evaluate the molecular basis behind low levels of FVII activity (FVII:C) levels in a cohort of Brazilian patients. A total...

Topics

Adolescent
Adult
Aged
Brazil
Child
Cohort Studies
Factor VII
Female
Genotype
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Young Adult

Source

Identifiers

PMID: 25828579
DOI: 10.1111/hae.12645

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