Article
Molecular and clinical aspects of factor VII deficiency.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 1998
Mariani G, Lo Coco L, Bernardi F, Pinotti M
Abstract excerpt
Factor VII (FVII) plays an important role in the initiation of blood coagulation, forming a complex with tissue factor (TF) which activates FIX and FX and FVII zymogen. FVII deficiency displays considerable phenotypic and molecular heterogeneity and there are inconsistencies between the clinical picture observed and the underlying clotting and molecular defects. We have reviewed the data available in the...
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