Article
Clinical phenotype and F7 gene genotype in 40 Tunisian patients with congenital factor VII deficiency.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2022
Ouardani Cherifa, Elmahmoudi Hejer, ELborgi Wejden, Gharbi Maroua, Meriem Achour, Gouider Emna
Abstract excerpt
Congenital factor VII (FVII) deficiency is an autosomal recessive bleeding disorder characterized by a weak phenotypic and genotypic correlation. This study aimed to determine the genetic alterations of 40 Tunisian patients and to evaluate their relationships with the collected clinical and biological data. Forty FVII-deficient Tunisian patients have been included in this study. First, diagnosis of the FVII...
Topics
- Factor VII
- Factor VII Deficiency
- Genotype
- Humans
- Introns
- Mutation
- Phenotype
- Tunisia