Article
Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective.
Internal medicine journal - 1 Apr 2015
Tye-Din J A, Cameron D J S, Daveson A J, Day A S, Dellsperger P, Hogan C, Newnham E D, Shepherd S J, Steele R H, Wienholt L, Varney M D
Abstract excerpt
The past decade has seen human leukocyte antigen (HLA) typing emerge as a remarkably popular test for the diagnostic work-up of coeliac disease with high patient acceptance. Although limited in its positive predictive value for coeliac disease, the strong disease association with specific HLA genes imparts exceptional negative predictive value to HLA typing, enabling a negative result to exclude coeliac disease...
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