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Article

Limited role of HLA DQ2/8 genotyping in diagnosing coeliac disease.

Scottish medical journal - 1 Feb 2017

Paul Siba P, Hoghton Matthew, Sandhu Bhupinder

Abstract excerpt

The European guidelines for diagnosing coeliac disease in children were revised in 2012. These recommend that in symptomatic children, a diagnosis of coeliac disease can be made without small-bowel biopsies provided their anti-tissue transglutaminase (anti-tTG) titre is >10 times of upper-limit-of-normal (>10×ULN) and anti-endomysial antibody is positive. In order to firm up the diagnosis in these children with...

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PMID: 28084899
DOI: 10.1177/0036933016689008

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