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Article

Clinical utility of celiac disease-associated HLA testing.

Digestive diseases and sciences - 1 Sept 2014

Pallav Kumar, Kabbani Toufic, Tariq Sohaib, Vanga Rohini, Kelly Ciaran P, Leffler Daniel A

Abstract excerpt

BACKGROUND: Negative predictive value (NPV) of celiac disease (CD)-related human leukocyte antigens (HLA) DQ2 and DQ8 approaches 100 % in individual patients. However, studies evaluating its exclusionary utility in patient groups are lacking. AIM: We aim to assess the performance of HLA testing when applied to patient groups with varying characteristics and propose evidence-based recommendations for its clinical...

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Identifiers

PMID: 24705698
DOI: 10.1007/s10620-014-3143-1
PMCID: PMC4149591

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