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Article

Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after γ-irradiation through Wnt/β-catenin pathway.

Carcinogenesis - 1 Jun 2015

Sakamaki Akira, Katsuragi Yoshinori, Otsuka Kensuke, Tomita Masanori, Obata Miki, Iwasaki Tomohiro, Abe Manabu, Sato Toshihiro, Ochiai Masako, Sakuraba Yoshiyuki, Aoyagi Yutaka, Gondo Yoichi, Sakimura Kenji, Nakagama Hitoshi, Mishima Yukio, Kominami Ryo

Abstract excerpt

SWI/SNF chromatin remodeling complexes constitute a highly related family of multi-subunit complexes to modulate transcription, and SWI/SNF subunit genes are collectively mutated in 20% of all human cancers. Bcl11b is a SWI/SNF subunit and acts as a haploinsufficient tumor suppressor in leukemia/...

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Identifiers

PMID: 25827435
DOI: 10.1093/carcin/bgv044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25827435-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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