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Article

Reconstitution of a prokaryotic minus end-tracking system using TubRC centromeric complexes and tubulin-like protein TubZ filaments.

Proceedings of the National Academy of Sciences of the United States of America - 14 Apr 2015

Fink Gero, Löwe Jan

Abstract excerpt

Segregation of DNA is a fundamental process during cell division. The mechanism of prokaryotic DNA segregation is largely unknown, but several low-copy-number plasmids encode cytomotive filament systems of the actin type and tubulin type important for plasmid inheritance. Of these cytomotive filaments, only actin-like systems are mechanistically well characterized. In contrast, the mechanism by which filaments of...

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Identifiers

PMID: 25825718
DOI: 10.1073/pnas.1423746112
PMCID: PMC4403160

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Source receipt: pubmed, retrieved 7 Sept 2026.

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