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Article

FcGR genetic polymorphisms and the response to adalimumab in patients with rheumatoid arthritis.

Pharmacogenomics - 1 Jan 2015

Dávila-Fajardo Cristina Lucía, van der Straaten Tahar, Baak-Pablo Rene, Medarde Caballero Catalina, Cabeza Barrera Jose, Huizinga Tom W, Guchelaar Henk-Jan, Swen Jesse J

Abstract excerpt

AIM: The aim of our study was to explore the potential of FcGR genetic polymorphisms as a predictor of adalimumab efficacy in rheumatoid arthritis (RA) patients. MATERIALS & METHODS: The study population was composed of 302 Dutch RA patients receiving adalimumab therapy. The FcGR2A (R131>H; rs1801274) and FcGR3A (F158>V; rs396991) genetic variants were genotyped using the TaqMan(®) allelic discrimination...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adalimumab
Share to Aged
Share to Arthritis, Rheumatoid
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Share to Polymorphism, Single Nucleotide
Share to Receptors, IgG
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Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 25823785
DOI: 10.2217/pgs.14.178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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