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Article

Association of FCGR2A with the response to infliximab treatment of patients with rheumatoid arthritis.

Pharmacogenetics and genomics - 1 May 2014

Montes Ariana, Perez-Pampin Eva, Narváez Javier, Cañete Juan D, Navarro-Sarabia Federico, Moreira Virginia, Fernández-Nebro Antonio, Del Carmen Ordóñez María, de la Serna Arturo R, Magallares Berta, Vasilopoulos Yiannis, Sarafidou Theologia, Caliz Rafael, Ferrer Miguel Angel, Joven Beatriz, Carreira Patricia, Gómez-Reino Juan J, Gonzalez Antonio

Abstract excerpt

OBJECTIVES: We aimed to assess a functional polymorphism in FCGR2A H131R, for association with the treatment response to Fc-containing inhibitors of tumor necrosis factor (TNF). METHODS: A total of 429 biologic-naive patients with rheumatoid arthritis collected in two sets (299 and 130) were treated during standard care with infliximab (INX), etanercept, or adalimumab. Response to the treatment was evaluated at...

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Share to Adalimumab
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal, Humanized

Share to Arthritis, Rheumatoid

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Source

Identifiers

PMID: 24667440
DOI: 10.1097/FPC.0000000000000042

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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