Article
Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Oct 2009
Cañete J D, Suárez B, Hernández M V, Sanmartí R, Rego I, Celis R, Moll C, Pinto J A, Blanco F J, Lozano F
Abstract excerpt
OBJECTIVE: Fc gamma receptor (Fc gammaR) polymorphism influences the affinity of the receptor for Ig, which may, in turn, affect the efficacy of Ig-based therapies. The relationship between functional single nucleotide polymorphisms (SNP) of the FCGR2A and FCGR3A genes and the response to anti-tu...
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