Article
Heterogeneity in vaccine immune response: the role of immunogenetics and the emerging field of vaccinomics.
Clinical pharmacology and therapeutics - 1 Dec 2007
Poland G A, Ovsyannikova I G, Jacobson R M, Smith D I
Abstract excerpt
Recent advances in the fields of immunology, genetics, molecular biology, bioinformatics, and the Human Genome Project have allowed for the emergence of the field of vaccinomics. Vaccinomics encompasses the fields of immunogenetics and immunogenomics as applied to understanding the mechanisms of heterogeneity in immune responses to vaccines. In this study, we examine the role of HLA genes, cytokine genes, and...
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