Impact of host genetic polymorphisms on vaccine induced antibody response.

doi:10.1080/21645515.2015.1119345

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Article

Impact of host genetic polymorphisms on vaccine induced antibody response.

Human vaccines & immunotherapeutics - 2 Apr 2016

Linnik Janina E, Egli Adrian

Abstract excerpt

Many host- and vaccine-specific factors modulate an antibody response. Host genetic polymorphisms, in particular, modulate the immune response in multiple ways on different scales. This review article describes how information on host genetic polymorphisms and corresponding immune cascades may be used to generate personalized vaccine strategies to optimize the antibody response.

Topics

Antibodies, Viral
Antibody Formation
Gene Expression
Humans
Immunity, Humoral
Influenza Vaccines
Influenza, Human
Measles
Measles Vaccine
Measles virus
Polymorphism, Single Nucleotide
Precision Medicine
Systems Biology
Vaccination
Vaccines

Source

Open in PubMed Open full text

Identifiers

PMID: 26809773
DOI: 10.1080/21645515.2015.1119345
PMCID: PMC4962936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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