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Article

Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.

Vaccine - 17 Jan 2011

Chen Jie, Liang Zhenglun, Lu Fengmin, Fang Xin, Liu Shuang, Zeng Ying, Zhu Fengcai, Chen Xiangmei, Shen Tao, Li Jie, Zhuang Hui

Abstract excerpt

It is well documented that 5-10% hepatitis B adult vaccinees are non- and hypo-responders and probably are not adequately protected against hepatitis B virus (HBV) infection. The sequence variations of genes involved in processes such as pathogen recognition, antigen processing and presentation, and differentiation/maturation of lymphocytes may affect the duration and intensity of protective humoral immune...

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Source

Identifiers

PMID: 21111021
DOI: 10.1016/j.vaccine.2010.11.023

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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