Article
Toll-like receptor 4 genetic variants and prognosis of breast cancer.
Tissue antigens - 1 Apr 2013
Yang C-X, Li C-Y, Feng W
Abstract excerpt
Despite the knowledge of many genetic alterations present in breast cancer, the complexity of this disease precludes placing its biology into a simple conceptual framework. Toll-like receptor 4 (TLR4) plays important roles in regulating innate immunity and may affect the development of cancers. Polymorphisms in TLR4 gene have been shown to be associated with impaired immune responses. Here, we investigated the...
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