Article
Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2013
McCracken Melissa N, Gschweng Eric H, Nair-Gill Evan, McLaughlin Jami, Cooper Aaron R, Riedinger Mireille, Cheng Donghui, Nosala Christopher, Kohn Donald B, Witte Owen N
Abstract excerpt
Positron emission tomography (PET) reporter genes allow noninvasive whole-body imaging of transplanted cells by detection with radiolabeled probes. We used a human deoxycytidine kinase containing three amino acid substitutions within the active site (hdCK3mut) as a reporter gene in combination wi...
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