Article
ACN9 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2015
Hill Shirley Y, Jones Bobby L, Zezza Nicholas, Stiffler Scott
Abstract excerpt
A previous genome-wide linkage study of alcohol dependence (AD) in the Pittsburgh-based multiplex family study found suggestive evidence for linkage on Chromosome 7q, a region in which the ACN9 gene is located. Using the same two generation Pittsburgh family data in which linkage was found, data for a third generation was added. The expanded sample included 133 pedigrees with 995 individuals. Finer mapping was...
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