Article
'Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.
Andrology - 1 May 2015
Punab A M, Grigorova M, Punab M, Adler M, Kuura T, Poolamets O, Vihljajev V, Žilaitienė B, Erenpreiss J, Matulevičius V, Laan M
Abstract excerpt
Luteinizing hormone (LH) is a pituitary heterodimeric glycoprotein essential in male and female reproduction. Its functional polymorphic variant (V-LH) is determined by two missense mutations (rs1800447, A/G, Trp8Arg; rs34349826, A/G, Ile15Thr) in the LH β-subunit encoding gene (LHB; 19q13.3; 1111 bp; 3 exons). Among women, V-LH has been associated with higher circulating LH and reduced fertility, but the...
Topics
- Aging
- Estonia
- Female
- Follicle Stimulating Hormone
- Gene Frequency
- Humans