Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of a natural variant of luteinizing hormone.

Human genetics - 1 Aug 2002

Liao W X, Goh H H, Roy A C

Abstract excerpt

Luteinizing hormone (LH) plays an important role in the gametogenesis in both sexes by promoting the production of sex steroid hormones in the testes and ovaries. We previously described a genetic variant (V) of LH resulted from a mutation (G1502A) in the LH beta-subunit gene, causing the glycine102serine change in the protein hormone. This variant was subsequently found to be associated with both male and female...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding, Competitive
Share to CHO Cells
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Vitro Techniques

Share to Luteinizing Hormone

Share to Precipitin Tests

Share to Progesterone

Share to Receptors, LH

Source

Identifiers

PMID: 12189497
DOI: 10.1007/s00439-002-0781-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of a natural variant of luteinizing hormone.PMID 12189497Read ↗

Functional study of a recombinant form of human LHbeta-subunit variant carrying the Gly(102)Ser mutation found in Asian populations.Semantic proximity Read ↗

A vital region for human glycoprotein hormone trafficking revealed by an LHB mutationSemantic proximity Read ↗

Synthesis, purification and structural and functional characterization of recombinant form of a common genetic variant of human luteinizing hormone.Semantic proximity Read ↗

Mutations and polymorphisms in gonadotropin genes.Semantic proximity Read ↗

Increased prevalence of luteinizing hormone beta-subunit variant in Japanese infertility patients.Semantic proximity Read ↗

'Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.Semantic proximity Read ↗

Occurrence and biological properties of a common genetic variant of luteinizing hormone.Semantic proximity Read ↗

Disparate response of wild-type and variant forms of LH to GnRH stimulation in individuals heterozygous for the LHbeta variant allele.Semantic proximity Read ↗

Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors.Semantic proximity Read ↗

A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence.Semantic proximity Read ↗

A new molecular variant of luteinizing hormone associated with female infertility.Semantic proximity Read ↗

Association of molecular variants of luteinizing hormone with male infertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.