Article
DEOD: uncovering dominant effects of cancer-driver genes based on a partial covariance selection method.
Bioinformatics (Oxford, England) - 1 Aug 2015
Amgalan Bayarbaatar, Lee Hyunju
Abstract excerpt
MOTIVATION: The generation of a large volume of cancer genomes has allowed us to identify disease-related alterations more accurately, which is expected to enhance our understanding regarding the mechanism of cancer development. With genomic alterations detected, one challenge is to pinpoint cancer-driver genes that cause functional abnormalities. RESULTS: Here, we propose a method for uncovering the dominant...
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