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Article

Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Apr 2015

Coates James, Jeyaseelan Asha K, Ybarra Norma, David Marc, Faria Sergio, Souhami Luis, Cury Fabio, Duclos Marie, El Naqa Issam

Abstract excerpt

BACKGROUND AND PURPOSE: We explore analytical and data-driven approaches to investigate the integration of genetic variations (single nucleotide polymorphisms [SNPs] and copy number variations [CNVs]) with dosimetric and clinical variables in modeling radiation-induced rectal bleeding (RB) and erectile dysfunction (ED) in prostate cancer patients. MATERIALS AND METHODS: Sixty-two patients who underwent curative...

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PMID: 25818395
DOI: 10.1016/j.radonc.2015.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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