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Article

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.

Nature communications - 30 Mar 2015

Gallina Irene, Colding Camilla, Henriksen Peter, Beli Petra, Nakamura Kyosuke, Offman Judith, Mathiasen David P, Silva Sonia, Hoffmann Eva, Groth Anja, Choudhary Chunaram, Lisby Michael

Abstract excerpt

DNA replication stress is a source of genomic instability. Here we identify changed mutation rate 1 (Cmr1) as a factor involved in the response to DNA replication stress in Saccharomyces cerevisiae and show that Cmr1--together with Mrc1/Claspin, Pph3, the chaperonin containing TCP1 (CCT) and 25 o...

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Source

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Identifiers

PMID: 25817432
DOI: 10.1038/ncomms7533
PMCID: PMC4389229

Genes

TCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25817432-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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