Article
Analyses of the TCR repertoire of MHC class II-restricted innate CD4⁺ T cells.
Experimental & molecular medicine - 27 Mar 2015
Kang Byung Hyun, Min Hye Sook, Lee You Jeong, Choi Bomi, Kim Eun Ji, Lee Jonghoon, Kim Jeong-Rae, Cho Kwang-Hyun, Kim Tae Jin, Jung Kyeong Cheon, Park Seong Hoe
Abstract excerpt
Analysis of the T-cell receptor (TCR) repertoire of innate CD4(+) T cells selected by major histocompatibility complex (MHC) class II-dependent thymocyte-thymocyte (T-T) interaction (T-T CD4(+) T cells) is essential for predicting the characteristics of the antigens that bind to these T cells and for distinguishing T-T CD4(+) T cells from other types of innate T cells. Using the TCR(mini) Tg mouse model, we show...
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