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Article

Learning to be tolerant: how T cells keep out of trouble.

Journal of internal medicine - 1 May 2009

Holländer G A, Peterson P

Abstract excerpt

A pool of immature T cells with a seemingly unrestricted repertoire of antigen specificities is generated life-long in the thymus. Amongst these cells are, however, thymocytes that express a strongly self-reactive antigen receptor and hence hold the potential to trigger autoimmunity. To prevent such an outcome, the thymus employs several independent but functionally related strategies that act in parallel to...

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Identifiers

PMID: 19382993
DOI: 10.1111/j.1365-2796.2009.02093.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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