Article
Mitochondrial tRNA mutations in patients with myelodysplastic syndromes.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jul 2016
Wang Hui-Rui, Li Ya-Wei, Wu Jun-Long, Guo Shu-Li
Abstract excerpt
Increasing evidence showed that mitochondria play an important role in the development of myelodysplastic syndromes (MDS). Mitochondrial dysfunctions caused by mitochondrial DNA mutations, especially mitochondrial tRNA mutations, were found to be associated with MDS in many studies. However, the link between a candidate mitochondrial tRNA mutation and MDS was not clear. In this study, we investigated the role of...
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