Article
The role of mitochondrial tRNA variants in female breast cancer.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Sept 2016
Meng Xian-Li, Meng Hua, Zhang Wei, Qin Yu-Hua, Zhao Ning-Min
Abstract excerpt
Mitochondrial tRNA (Mt-tRNA) variants have been found to be involved in the carcinogenesis of breast cancer. These tRNAs, which played critical roles in mitochondrial protein synthesis, were important regulators in tumorigenesis. Distinguishing the polymorphisms or mutations in mt-tRNA genes was still puzzling for the clinicians and geneticists when confronted with the breast cancer. In this study, we performed a...
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