Mitochondrial DNA variations in myelodysplastic syndrome.

Abstract excerpt

There have been significant advances in the understanding of mitochondrial function and their contribution to human disease in the last few years. The myelodysplastic syndromes (MDSs) are heterogeneous group of disorders characterized by clonal proliferation of multipotent hematopoietic cells with ineffective hematopoiesis. They are often associated with evidence of mitochondrial dysfunction. Studies have shown...

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