Article
Mitochondrial DNA mutations may not be frequent in asthenospermic infertile men.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2016
Wang Junkai, Chen Jie, Cui Xingang, Liu Yushan, Yin Lei, Li Yao, Chen Lu, Xu Danfeng, Gao Yi
Abstract excerpt
Mutations in mitochondrial DNA were implicated to be associated with male infertility. Due to its high mutation rate, mtDNA defects may occur at any nucleotide of its 16,569 bp sequence. In this study, we analyzed a recent paper concerning the role of mtDNA variations in asthenospermic infertile men, we found that mtDNA mutation was a frequent event in male infertility. However, some polymorphisms in gene...
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