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Article

Screening for Mitochondrial tRNA Mutations in 318 Patients with Dilated Cardiomyopathy.

Human heredity - 1 Jan 2022

Qi Yujuan, Wu Zhenhua, Bai Yaobang, Jiao Yan, Li Peijun

Abstract excerpt

OBJECTIVES: Dilated cardiomyopathy (DCM) is a complex cardiovascular disease with unknown etiology. Although nuclear genes play active roles in DCM, mitochondrial dysfunction was believed to be involved in the pathogenesis of DCM. The objective of this study was to analyze the association between mitochondrial tRNA (mt-tRNA) mutations and DCM. MATERIALS AND METHODS: We performed a mutational analysis of mt-tRNA...

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Share to Adenosine Triphosphate
Share to Cardiomyopathy, Dilated
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Reactive Oxygen Species

Share to RNA, Mitochondrial

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Source

Identifiers

PMID: 34991096
DOI: 10.1159/000521615

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TH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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