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Article

Mutant p53 expression in fallopian tube epithelium drives cell migration.

International journal of cancer - 1 Oct 2015

Quartuccio Suzanne M, Karthikeyan Subbulakshmi, Eddie Sharon L, Lantvit Daniel D, Ó hAinmhire Eoghainín, Modi Dimple A, Wei Jian-Jun, Burdette Joanna E

Abstract excerpt

Ovarian cancer is the fifth leading cause of cancer death among US women. Evidence supports the hypothesis that high-grade serous ovarian cancers (HGSC) may originate in the distal end of the fallopian tube. Although a heterogeneous disease, 96% of HGSC contain mutations in p53. In addition, the "p53 signature," or overexpression of p53 protein (usually associated with mutation), is a potential precursor lesion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25810107
DOI: 10.1002/ijc.29528
PMCID: PMC4503498

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutant p53 expression in fallopian tube epithelium drives cell migration.PMID 25810107Read ↗

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TP53 loss initiates chromosomal instability in fallopian tube epithelial cells.Semantic proximity Read ↗

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