Article
prdm1a functions upstream of itga5 in zebrafish craniofacial development.
Genesis (New York, N.Y. : 2000) - 1 Jan 2000
LaMonica Kristi, Ding Hai-lei, Artinger Kristin Bruk
Abstract excerpt
Cranial neural crest cells are specified and migrate into the pharyngeal arches where they subsequently interact with the surrounding environment. Signaling and transcription factors, such as prdm1a regulate this interaction, but it remains unclear which specific factors are required for posterior pharyngeal arch development. Previous analysis suggests that prdm1a is required for posterior ceratobranchial...
Topics
- Animals
- Animals, Genetically Modified
- DNA-Binding Proteins
- Embryo, Nonmammalian
- Face
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Integrin alpha5
- Mutation
- Nuclear Proteins
- Positive Regulatory Domain I-Binding Factor 1