Article
Dlx5 regulates regional development of the branchial arches and sensory capsules.
Development (Cambridge, England) - 1 Sept 1999
Depew M J, Liu J K, Long J E, Presley R, Meneses J J, Pedersen R A, Rubenstein J L
Abstract excerpt
We report the generation and analysis of mice homozygous for a targeted deletion of the Dlx5 homeobox gene. Dlx5 mutant mice have multiple defects in craniofacial structures, including their ears, noses, mandibles and calvaria, and die shortly after birth. A subset (28%) exhibit exencephaly. Ectodermal expression of Dlx5 is required for the development of olfactory and otic placode-derived epithelia and...
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