Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study.

doi:10.1111/ajt.13122

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Article

Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 May 2015

Shabir S, Girdlestone J, Briggs D, Kaul B, Smith H, Daga S, Chand S, Jham S, Navarrete C, Harper L, Ball S, Borrows R

Abstract excerpt

Recent cross-sectional studies suggest an important role for transitional B lymphocytes (CD19 + CD24hiCD38hi) in promoting transplant tolerance, and protecting from late antibody-mediated rejection (ABMR). However, prospective studies are lacking. This study enrolled 73 de novo transplant recipients, and collected serial clinical, immunological and biochemical information over 48 ± 6 months. Cell phenotyping was...

Topics

Adult
Antibodies
B-Lymphocytes
Biomarkers
Biopsy
Female
Graft Rejection
HLA Antigens
Humans
Immunity, Humoral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunophenotyping

Immunosuppressive Agents

Kidney Transplantation

Male

Middle Aged

Patient Compliance

Phenotype

Prospective Studies

Source

Open in PubMed

Identifiers

PMID: 25808898
DOI: 10.1111/ajt.13122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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