Article
Regulation of T- and B-cell interactions determines the clinical phenotype associated with donor-specific antibodies.
Kidney international - 1 May 2022
Basu Sumoyee, Dorling Anthony
Abstract excerpt
The cellular mechanisms that regulate donor-specific antibody formation and antibody-mediated rejection remain unknown. In this issue, Louis et al. report that specific T-regulatory cell and B-regulatory transitional cell subsets are concomitantly diminished in patients with donor-specific antibody and consequent antibody-mediated rejection and advance alterations in specific cytokines and costimulatory molecules...
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