Article
Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients.
Transplantation - 1 Nov 2017
Gao Baoshan, Gu Yiming, Rong Chunshu, Moore Carolina, Porcheray Fabrice, Wong Waichi, Preffer Frederic, Saidman Susan L, Fu Yaowen, Cosimi Benedict, Sachs David H, Kawai Tatsuo, Sykes Megan, Zorn Emmanuel
Abstract excerpt
BACKGROUND: Previous studies identified B cell gene signatures and predominance of specific B cell subsets as a marker of operational tolerance after kidney transplantation. These findings suggested a role for B cells in the establishment or maintenance of tolerance. Here we analyzed B cell recovery in 4 subjects, 3 of whom achieved tolerance after combined kidney/bone marrow transplantation. METHODS: Peripheral...
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