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Article

Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence.

Brain pathology (Zurich, Switzerland) - 1 Jan 2016

Videla Richardson Guillermo Agustín, Garcia Carolina Paola, Roisman Alejandro, Slavutsky Irma, Fernandez Espinosa Damián Darío, Romorini Leonardo, Miriuka Santiago Gabriel, Arakaki Naomi, Martinetto Horacio, Scassa María Elida, Sevlever Gustavo Emilio

Abstract excerpt

Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined. In this study, we established several GSC-enriched cell lines (GSC-ECLs) from high-grade gliomas. The expansion of these cells as adherent monolayers, and not as floating neurospheres, enabled a thorough study of the phenotypic changes that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25808628
DOI: 10.1111/bpa.12263
PMCID: PMC8029422

Genes

GSC
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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