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Article

Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma.

Neoplasia (New York, N.Y.) - 1 Apr 2017

Xi Guifa, Best Benjamin, Mania-Farnell Barbara, James Charles David, Tomita Tadanori

Abstract excerpt

Human glioma, in particular, malignant forms such as glioblastoma exhibit dismal survival rates despite advances in treatment strategies. A population of glioma cells with stem-like features, glioma cancer stem-like cells (GCSCs), contribute to renewal and maintenance of the tumor cell population and appear responsible for chemotherapeutic and radiation resistance. Bone morphogenetic protein 4 (BMP4), drives...

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Source

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Identifiers

PMID: 28278424
DOI: 10.1016/j.neo.2017.01.006
PMCID: PMC5342987

Genes

BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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