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Article

Astrocytes influence medulloblastoma phenotypes and CD133 surface expression.

PloS one - 1 Jan 2020

Gronseth Emily, Gupta Ankan, Koceja Chris, Kumar Suresh, Kutty Raman G, Rarick Kevin, Wang Ling, Ramchandran Ramani

Abstract excerpt

The medulloblastoma (MB) microenvironment is diverse, and cell-cell interactions within this milieu is of prime importance. Astrocytes, a major component of the microenvironment, have been shown to impact primary tumor cell phenotypes and metastasis. Based on proximity of MB cells and astrocytes in the brain microenvironment, we investigated whether astrocytes may influence MB cell phenotypes directly. Astrocyte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32628717
DOI: 10.1371/journal.pone.0235852
PMCID: PMC7337293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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