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Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture

26 Mar 2015

Abstract excerpt

Fascin, a highly conserved actin-bundling protein, localizes and functions at new cellular sites in both Drosophila and multiple mammalian cell types. During Drosophila follicle development, in addition to being cytoplasmic, Fascin is in the nuclei of the germline-derived nurse cells during stages 10B-12 (S10B-12) and at the nuclear periphery during stage 13 (S13). This localization is specific to Fascin, as...

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PMID: 25808493
DOI: 10.1091/mbc.e14-09-1384

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