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Article

MYC and Human Telomerase Gene (TERC) Copy Number Gain in Early-stage Non–small Cell Lung Cancer

26 Nov 2013

Abstract excerpt

OBJECTIVES: We investigated the frequency of MYC and TERC increased gene copy number (GCN) in early-stage non-small cell lung cancer (NSCLC) and evaluated the correlation of these genomic imbalances with clinicopathologic parameters and outcome. MATERIALS AND METHODS: Tumor tissues were obtained from 113 resected NSCLCs. MYC and TERC GCNs were tested by fluorescence in situ hybridization (FISH) according to the...

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Share to Epigenetics and DNA Methylation
Share to Genomic variations and chromosomal abnormalities
Share to Telomeres, Telomerase, and Senescence

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PMID: 25806711
DOI: 10.1097/coc.0000000000000012

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