Article
The genomic and epigenomic landscape in thymic carcinoma.
Carcinogenesis - 26 Oct 2017
Saito Motonobu, Fujiwara Yutaka, Asao Tetsuhiko, Honda Takayuki, Shimada Yoko, Kanai Yae, Tsuta Koji, Kono Koji, Watanabe Shunichi, Ohe Yuichiro, Kohno Takashi
Abstract excerpt
Thymic carcinoma (TC) is a rare cancer whose genomic features have been examined in only a limited number of patients of European descent. Here, we characterized both genomic and epigenomic aberrations by whole exome sequencing, RNA sequencing, methylation array and copy number analyses in TCs from Asian patients and compared them with those in TCs from USA/European patients. Samples analyzed were 10 pairs of...
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