Article
Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system.
MicrobiologyOpen - 1 Jun 2015
Adamiak Paul, Calmettes Charles, Moraes Trevor F, Schryvers Anthony B
Abstract excerpt
Neisseria meningitidis inhabits the human upper respiratory tract and is an important cause of sepsis and meningitis. A surface receptor comprised of transferrin-binding proteins A and B (TbpA and TbpB), is responsible for acquiring iron from host transferrin. Sequence and immunological diversity divides TbpBs into two distinct lineages; isotype I and isotype II. Two representative isotype I and II strains, B16B6...
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