Article
Neisseria adhesin A variation and revised nomenclature scheme.
Clinical and vaccine immunology : CVI - 1 Jul 2014
Bambini Stefania, De Chiara Matteo, Muzzi Alessandro, Mora Marirosa, Lucidarme Jay, Brehony Carina, Borrow Ray, Masignani Vega, Comanducci Maurizio, Maiden Martin C J, Rappuoli Rino, Pizza Mariagrazia, Jolley Keith A
Abstract excerpt
Neisseria adhesin A (NadA), involved in the adhesion and invasion of Neisseria meningitidis into host tissues, is one of the major components of Bexsero, a novel multicomponent vaccine licensed for protection against meningococcal serogroup B in Europe, Australia, and Canada. NadA has been identified in approximately 30% of clinical isolates and in a much lower proportion of carrier isolates. Three protein...
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