Article
Role of transferrin receptor from a Neisseria meningitidis tbpB isotype II strain in human transferrin binding and virulence.
Infection and immunity - 1 Jun 2004
Renauld-Mongénie Geneviève, Poncet David, Mignon Michèle, Fraysse Sophie, Chabanel Christophe, Danve Bernard, Krell Tino, Quentin-Millet Marie-José
Abstract excerpt
Neisseria meningitidis acquires iron through the action of the transferrin (Tf) receptor, which is composed of the Tf-binding proteins A and B (TbpA and TbpB). Meningococci can be classified into isotype I and II strains depending on whether they harbor a type I or II form of TbpB. Both types of TbpB have been shown to differ in their genomic, biochemical, and antigenic properties. Here we present a comparative...
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