Article
Sequence variability of FrpB, a major iron-regulated outer-membrane protein in the pathogenic neisseriae.
Microbiology (Reading, England) - 1 Nov 1996
van der Ley P, van der Biezen J, Sutmuller R, Hoogerhout P, Poolman J T
Abstract excerpt
The FrpB protein from pathogenic neisseriae is a 77 kDa iron-regulated outer-membrane protein that belongs to the family of TonB-dependent receptors and may have potential as a vaccine component. Comparison between the frpB gene from three different meningococcal strains and a published gonococcal one revealed that the region from residues 350 to 390 displays pronounced sequence variability. In a model for the...
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