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Article

Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds.

PLoS pathogens - 1 Mar 2015

Yang Wan-Lin, Kouyos Roger D, Böni Jürg, Yerly Sabine, Klimkait Thomas, Aubert Vincent, Scherrer Alexandra U, Shilaih Mohaned, Hinkley Trevor, Petropoulos Christos, Bonhoeffer Sebastian, Günthard Huldrych F

Abstract excerpt

Transmission of drug-resistant pathogens presents an almost-universal challenge for fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time. It is generally believed that differential TDRM-persistence is caused, at least...

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Identifiers

PMID: 25798934
DOI: 10.1371/journal.ppat.1004722
PMCID: PMC4370492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25798934-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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