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Article

Single-base mismatch discrimination by T7 exonuclease with target cyclic amplification detection.

Chemical communications (Cambridge, England) - 18 Feb 2015

Wu Zhen-Kun, Zhou Dian-Ming, Wu Zhan, Chu Xia, Yu Ru-Qin, Jiang Jian-Hui

Abstract excerpt

T7 exonuclease is reported for the first time to have high specificity in discriminating single-base mismatch and utilized for developing a target cyclic amplification biosensor strategy for sensitive SNP detection based on graphene oxide quenching of uncleaved probes.

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Share to Polymorphism, Single Nucleotide
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25594081
DOI: 10.1039/c4cc09984b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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