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Article

Susceptibility variants in the CD58 gene locus point to a role of microRNA-548ac in the pathogenesis of multiple sclerosis.

Mutation research. Reviews in mutation research - 1 Jan 2000

Hecker Michael, Fitzner Brit, Blaschke Jana, Blaschke Paul, Zettl Uwe Klaus

Abstract excerpt

Multiple sclerosis (MS) is a neurological immune-driven disease of unknown etiology. A genetic contribution to MS susceptibility is well established and more than 100 associated genomic regions have been identified. However, there is little understanding of how individual genetic variants are involved in the pathogenesis of MS. Single nucleotide polymorphisms (SNPs) within the first intron of CD58 have been...

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Identifiers

PMID: 25795118
DOI: 10.1016/j.mrrev.2014.10.002

Genes

DGCR8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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