Article
In silico prioritisation of microRNA-associated common variants in multiple sclerosis.
Human genomics - 30 Mar 2023
Fashina Ifeolutembi A, McCoy Claire E, Furney Simon J
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have highlighted over 200 autosomal variants associated with multiple sclerosis (MS). However, variants in non-coding regions such as those encoding microRNAs have not been explored thoroughly, despite strong evidence of microRNA dysregulation in MS patients and model organisms. This study explores the effect of microRNA-associated variants in MS, through the...
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